Full Name: Nexera Method Scouting System
Team: Shimadzu Scientific Instruments, Columbia, MD
Status: Active, available
Debut: Pittcon 2014
Field Position: R&D and QA/QC Environments
Skill Set: Improves HPLC/UHPLC method development productivity
• Capable of automatically investigating up to 96 combinations of mobile phases, gradients and columns
• Transfer program allows ultra-high-speed conditions to be transferred to conventional conditions
• Performs mobile phase purging and equilibration automatically for fast mobile phase switching and reliable data acquisition.
Regulatory Profile: Supports proactive quality and compliance administration.
Coach’s Notes: “Equipped with two pumps—each with a quaternary valve—Shimadzu’s Nexera Method Scouting System allows analysts to run binary gradients with 16 different solvent pairs. When combined with a robust high-pressure resistant column selection valve, which holds up to six conventional or UHPLC columns, the system can investigate up to 96 unique separation conditions per sample. A transfer program allows ultra-high-speed conditions to be transferred to conventional conditions, making the system suitable for both R&D and QA/QC applications.”
Scout’s Notes: "Dedicated software employs a graphical user interface and automated controls for simple creation of a scouting batch. It performs mobile phase purging and equilibration automatically for fast mobile phase switching and reliable data acquisition. In addition, scouting schemes can be prioritized based on laboratory policy. The system automatically calculates the required amount of each mobile phase to avoid shortages, and automatically controls upper pressure limits to eliminate column degradation during testing. In addition, it provides estimated completion times, allowing operators to conduct testing according to their work schedules."
Team Resources: Shimadzu Scientific Instruments (SSI) is the American subsidiary of Shimadzu Corp., headquartered in Kyoto, Japan. Founded in 1875, Shimadzu is a $3 billion multinational corporation with three major divisions: Medical Diagnostics, Aerospace/Industrial and Analytical Instruments. In the U.S., SSI has a network of more than 50 locations providing local and regional sales, service and technical support.