Click here for larger image.GE Analytical Instruments, a division of GE Water & Process Technologies, introduces its new Sievers 500 RL On-Line TOC Analyzer. Utilizing Sievers' proven laboratory TOC (total organic carbon) measurement technology, the 500 RL was designed to deliver science-based risk management capability to the production floor for Process Analytical Technology (PAT) and other quality initiatives such as real-time pharmaceutical water release and on-line cleaning validation.The reagentless Sievers 500 RL On-Line TOC Analyzer incorporates features such as the Super iOS that automate high-risk and frequently performed activities, significantly reducing labor costs and eliminating the delays associated with laboratory analyses. The new Sievers Super iOS standards introduction device fully automates the delivery of multiple standards.Featuring four vial ports that accept pre-built vial set cartridges, the Super iOS automates all system protocols including system suitability, verification and calibration. The Super iOS cartridges contain an embedded memory chip that stores and securely captures each standard's type, concentration, lot number and expiration. That metadata is attached to the analytical results of the protocol. Data security is further enhanced by the availability of encrypted data output from the 500 RL. The Sievers DataShare 500 software allows users to open the 500 RLs encrypted data files for secure viewing and customized data report generation.The Sievers 500 RL provides continuous quality assurance for on-line pharmaceutical water release and cleaning validation, supporting the industry focus on automating processes critical to improving manufacturing efficiencies. The Sievers 500 RL is also designed for continuous monitoring of organics in ultrapure water for the microelectronics and power industries.The 500 RL Analyzer shares many productivity and ease-of-use features of other Sievers TOC Analyzers, including 12-month calibration stability, a color touch-screen display, USB port, and minimal maintenance (a few hours per year). With a wide operating range of 0.03 ppb to 2,500 ppb, the 500 RL also measures USP <645> conductivity. The optional Sievers DataGuard 500 software facilitates 21 CFR Part 11 compliance, including system security assurance, electronic signature capability, and the creation of an automatic, independently generated audit trail.The Sievers 500 RL can be seen at PITTCON 2006, Booth No. 2602 and 2603, and INTERPHEX 2006, Booth No. 1809.