Eksigent, a developer of advanced low-flow fluid delivery technologies for drug discovery and other life science applications, has added a NanoLC MALDI Spotting System to its nanoflow chromatography product line. Featuring the new Ekspot spotter, the new system complements the company's existing offerings for nanospray mass spectrometry (MS) proteomics analysis. Integration of the Ekspot with the NanoLC provides single-point control from the Eksigent software. The powerful new tool enables the analysis of complex protein and peptide samples with MALDI MS.

"This new capability enables customers to use our powerful NanoLC systems in MALDI applications," explained Remco van Soest, product manager for Eksigent. "Our NanoLC is already the leading platform for proteomics applications, and many customers have been using our LC with a third-party spotter. Now we can provide them with a solution that is fully integrated and optimized for our NanoLC."

The Ekspot spotter/fraction collector deposits fractions eluted from the NanoLC onto a MALDI plate, while a built-in pump automatically adds the matrix. High positioning accuracy ensures consistent spotting with maximum resolution. The high-capacity system stores up to 16 MALDI-targets for high-throughput applications.

By eliminating flow splitting, Eksigent's proprietary microfluidic technology improves reproducibility and sensitivity and eliminates solvent waste. The NanoLC's precise microscale flow control runs HPLC gradients at rates as low as 20 nL per minute.

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