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The Desired State: PAT and the Road to Enlightenment

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Pharmaceutical processing & engineering: By focusing on the pharmaceutical manufacturing process, ASTM standards for process analytical technology (PAT) promise to bring engineering rigor and proactive decisionmaking to pharmaceutical quality.

Stable Isotopes Find a New Role in PAT

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Pharmaceutical processing & engineering: In this article, we discuss how isotopic analysis can be used to track the isotopic fractionation that occurs in synthetic pharmaceutical manufacturing processes. We also present and discuss preliminary results of J&J studies using isotopic analysis to ...

S88 Redefines Clean in Place Operations

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Object-oriented programming and class-based programming simplify design, testing and validation of reusable modules, such as those found in CIP processes.

Open Batch Control: Not Quite Plug-and-Play, But Getting Closer

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Pharmaceutical processing & engineering: At May’s World Batch Forum, BMS and Pfizer discussed the S88 open batch control standard and how they’re using it.

Career Advice: Dork or Diva? What NOT to Wear to Your Next Job Interview

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Pharmaceutical industry career advice: You’re targeting the right job, so make sure you’ve got the right look.

Using Open Control to Optimize WFI

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Pharmaceutical processing & engineering: Sanofi-Aventis used the S88 open batch control standard and a distributed HMI to automate Water for Injection, boosting efficiency and compliance.

From the Editor: Think Like An Engineer

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Pharmaceutical processing & engineering: In the future, quality will depend more closely, as it does in other industries, on process control, instrumentation and mathematical modeling. Like it or not, nonengineers, the era of the geek is dawning

Smarter than “Smart Labels”?

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Radio frequency identification (RFID) is gaining wider adoption among consumer packaged goods (CPG) suppliers, driven in large part by a recent mandate by Wal-Mart Stores Inc.

The RFID Workforce: A Gold Rush Ahead

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RFID Tribe created this in-depth report on the RFID workforce – the first report of its kind. This report describes those individuals taking advantage of an emerging technology – radio frequency identification (RFID) technology.

Using RFID to Effectively Support the Pharmaceutical Supply Chain

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To get the most out of radio frequency identification (RFID), manufacturers must embrace the technology, but understand its limitations. Darren Suprina, chief security architect at Verifichi, offers wisdom and guidance.

Where Are the Academics?

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Outside of M.I.T., academia hasn’t really been invited to the RFID party. Industry needs their objectivity, says Daniel Deavours, head of the RFID Alliance Lab at the University of Kansas.

Sound Off

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Pharmaceutical processing & engineering: Sound Off is PharmaManufacturing.com's blog, written by industry insiders and our editors. This Web log examines the industry and its manufacturing facilities to launch frank discussion of key issues that affect everyone in pharmaceutical manufacturing.

Getting Big Protection with Small Technologies

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Pharmaceutical Processing & Engineering: Covert nanotechnology measures are key to a multi-layered approach.

Less is More in API Process Development

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API manufacturers in India and China have grasped the need for simplicity, while U.S. process chemists continue along their costly and complex path. Girish Malhotra shares recommendations for improved API process development.

Mind Over Metal: Master Impurities

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Pharmaceutical processing & engineering: Metal detectors and x-ray machines are vying for space on the manufacturing line, though both figure to retain key niches.

Black Belt Not Required: Where Did You Learn How to Drive?

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Data-driven management yields valuable business metrics to support your team's accomplishments. The key is to identify the types of data needed, using practicality as a watchword.

Desperately Seeking Safety: Making Sense of Sterile Package Defects

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Medical device/drug packaging: An Institute of Packaging Professionals task force has launched an effort to determine what packaging defect sizes are dangerous for device and drug/device products.

Need RFID? Start Here.

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Pharmaceutical processing & engineering: RFID represents one of the most promising new technologies for supply-chain management, but also one of the most time-consuming to implement. That’s why several companies are now offering "RFID starter kits."

RFID: Where Do We Stand?

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RFID has been a hot topic of conversation, thanks to the mega-retailers, the DOD and the FDA. But actual adoption of the technology has been tepid at best.

Beyond Gen2: The Next Step Toward RFID Ubiquity

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Drug packaging: By the fall of 2005, serious quantities of production level Gen2-compliant RFID tags will become available. This represents a major milestone for deployment of passive tags. Full implementations of the Gen2 standard (generally referred to as the Dense Reader implementation) ...

The State of E-Pedigree Laws

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Drug packaging: Coming to a state near you, laws which require certified drug authentication. Florida is leading all states the stringency of its drug pedigree laws. Florida law, effective July 2006, will require pedigrees for all drugs, meaning products must be authenticated and certified — ...

Purdue Pharma Blazes a Trail for Drug Security

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Drug packaging: Purdue Pharma is RFID-tagging bottles of OxyContin and Palladone, taking product safety and supply chain oversight to new levels.

Surf and Search: How to Find a Job on the Web

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Job hunting in the pharmaceutical industry: So you’re ready to search for a job, and target your next career step. There are a number of resources available to you on the Internet, and by using them strategically you can have success.

Therapeutic Dose: Riding the Indian Wave

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The pharmaceutical industry in India is changing the global business and industrial landscape more than we can imagine, says Jim Pinto, renowned industrial analyst and self-proclaimed futurist. What drives India is not cheap labor, Pinto says, but hunger — hunger for jobs and higher wages, but ...

Does Better Packaging Equal Better Patient Compliance?

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Researchers have confirmed a common-sense notion: patient compliance with a prescribed medication regimen increases when the drug packaging is easier to read and understand.

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