The latest issue of the journal 
Angewandte Chemie ran an article by Tel Aviv professors Shapiro and Vigalok on "green" pharmaceutical process development and cases in which water could replace some key solvents.  More (but not much more) on the process 
here and 
more information from InPharmaTechnologist.com.
Meanwhile, today brought 
news of a green chemistry collaboration involving Rowan University students and Pfizer, results of which will be reported in two weeks at the Green Chemistry meeting in Washington, D.C.