Benefit From Better Pharmaceutical Processing Control

Automating valve operation makes continuous processing possible

By Helge Hornis, Ph.D., Manager Intelligent Systems Group, Pepperl+Fuchs

Pharmaceutical processing is all about controlling flow, mixtures, temperatures, pressures, and a number of other variables that influence the quality and yield of the final product. Automating the control and verification of these parameters not only increases quality and yield, but also has the potential to accelerate manufacturing processes. This is where a modern controls strategy comes in. Automating valve operation makes continuous processing possible where previously batch handling was preferred.

Imagine a system with a large number of valves and mixers. From the point of view of a distributed control system (DCS) or programmable logic controller (PLC), these devices are controlled by setting outputs. Furthermore, consider the system to have a large number of flow meters, pressure gauges and temperature probes. Generally speaking, these are the inputs to the control system. Historically, input and output devices were directly connected to suitable I/O cards on DCS or PLC backplanes. Because pharmaceutical plants tend to be large, the necessary cable runs are significant. Running large amounts of cable makes installation time-consuming and costly. Besides the cost of the cable, cable bridges, conduit, field-mounted junction boxes, along with the necessary labeling, are other cost drivers that make such installations complex, expensive, difficult to maintain and challenging to expand or update.

A well-structured controls architecture based on a modern industrial network has the ability to deal with those negatives and offer the pharmaceutical industry flexible solutions. These solutions not only reduce the initial implementation expenses and cost of ownership, but also add the ability to quickly modify the process by simplifying the addition of supplementary process signals.

For nearly 20 years, AS-Interface has been the preferred control network for low-level digital and analog data. Worldwide, over 24 million/1/ field devices have been installed. These field devices control everything from roller-coasters to automotive assembly lines to chemical plants. Pharmaceutical applications specifically can benefit from this technology, as it addresses many issues that plant operators are frequently faced with. How can processors benefit? The following should offer some enlightenment:















AS-Interface uses a 2-conductor power and communication cable. This alone simplifies installation and startup. In contrast to all other networking solutions availabe, AS-Interface does not require the network to have a predefined topology. Instead, branching is allowed without limitation. As seen in Figure 1, it is even possible to add child branches to parent branches. Since AS-Interface was originally designed with mainly discrete factory automation applications in mind, connecting I/O modules to the network had to be fast, easy and reliable. This goal was accomplished by using an insulation displacement technology where piercing needles penetrate a flat, 2-conductor, unshielded cable to create the necessary electrical connection. While process automation applications can take advantage of this installation method, it is common to see conventional round cable being used in most applications. Since the AS-Interface was designed for use with unshielded cable, it’s recommended system designers use lower cost, flexible unshielded round cable.

Creating a new network branch does not require special hardware; two simple wiring terminals will do just fine. Still, in cases where multiple I/O devices are to be placed in an area, AS-Interface suppliers are now offering junction blocks with M12 quick disconnects (Figure 2).









No installation is 100% correct on day one; expansions and modifications are facts of life. AS-Interface supports change by allowing modules to be connected or removed from the network while under power. Imagine that a new valve must be installed. The process could not be simpler. Technicians simply install the new valve and assign its desired network address using a handheld addressing tool; essentially a calculator-shaped unit with a small display and a few push buttons. The valve can then be connected to network. From the point of view of the DCS or PLC, the new valve is unexpected, resulting in some kind of error indication. But the important fact is that control of any of the previously present I/Os is not inhibited. The control system simply reports the fact that the hardware configuration is not what it used to be. With the valve connected, it is still necessary to accept the valve in the AS-Interface configuration and make logic changes.

Programmers will like the fact that in virtually all instances, it is not necessary to manually modify hardware configuration files. Most typically, the AS-Interface field data is transferred to the DCS/PLC through a gateway. In the past, PROFIBUS, DeviceNet, and Modbus were the preferred solutions. For several years now, Ethernet approaches like PROFINET, EtherNet/IP and Modbus/TCP have gained popularity. Because these gateways are large I/O, single module devices to the DCS/PLC, changes on the AS-Interface side are automatically available. For instance, the I/O occupied by the valve we just added had already been mapped in the control system. The data bits simply did not change. With the valve installed and accepted on the AS-Interface network (typically accomplished by pressing buttons on the gateway), the valve data is immediately available in the DCS/PLC I/O table.

When evaluating maintenance advantages, one needs to distinguish between maintenance operations due to failures as well as preventive maintenance. Every failure of an electronic component will result in the loss of control. The ability to correct such failures is critical. AS-interface offers unparalleled ease and speed. The AS-Interface standard requires every gateway to be able to perform Automatic Single Node Replacement.

Specifically, when a valve, pressure transducer or temperature probe fails, maintenance only has to remove the failed component and replace it with an identical, new off-the-shelf device. This operation does not require any additional tools and it is not necessary to know the address of the failed device. Once the new device gets connected, the gateway identifies it as the replacement for the failed unit, assigns the correct address and starts data exchange. This process takes only seconds.

Preventive maintenance, especially on valves, is quite common. In most cases, the valve needs to be disconnected from the network. AS-Interface devices, including valves, can be disconnected while the network is powered up. As soon as the valve has been taken off, the gateway will report a configuration error to the DCS/PLC. Modern gateways utilize graphical displays with text messages informing the operator about the missing device. Note that all other inputs and outputs remain operational. Once the valve has been serviced and is ready, it is simply reconnected to the network. The gateway automatically reestablishes communication.

These kinds of on/off valves are frequently controlled by AS-Interface. Because small electrical loads can be powered directly from the yellow communication cable, only two leads must be connected. AS-Interface modules can have up to four inputs and four outputs, allowing the AS-interface module that is part of a valve to control the state of the valve and collect sensor input states. Spring return valves require only one output and are equipped with two end-point sensors. This leaves two additional input data bits that can be used for other operations. Depending on the design of the AS-Interface, device diagnostics information like coil lead breakage can then be reported to the DCS/PLC without increasing the installation complexity.

Since the implementation of AS-Interface in quarter-turn valves is inexpensive and the reduction of installation complexity and cost is significant, these types of valves are found in many process automation and pharmaceutical installations. Several suppliers offer valves with integrated AS-Interface electronics. In case a suitable valve cannot be found or is not desirable, third-party valve control modules are available (Figure 3). These control modules typically fit the standard bolt patterns found on most quarter-turn valves.


Proportional valves offer finer control than quarter-turn on/off valves and are controlled by an analog signal from the DCS/PLC. Compared to on/off signals, analog data is considerably more susceptible to plant noise. Installers must take special care, use high-quality shielded cables and consider noise sources along the cable path. In conventional hard-wired, point-to-point installations the length of such analog cable can be rather extensive. Consequently, this maxim generally applies: “The longer the cable, the more likely that data will be corrupted.” This is particularly true then dealing with 0-10V, PT100, or thermocouple temperature signals. AS-Interface addresses both of those issues. Instead of bringing analog data back to the DCS/PLC, an analog module will be mounted as close as possible to the field device. Doing this reduces the length of shielded cable necessary and simplifies the installation. And once the data gets converted to digital signal, noise will not be able to affect measurement values (analog inputs) or valve set points (analog outputs). Because the analog values are transmitted as digitized data bits via AS-Interface, all inherent data protection methods are applied.

Published in the October 2013 edition of Pharmaceutical Manufacturing magazine

1) SPS-Magazin, 08/11/2012, Einfach – sicher –international (

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