Multivariate Calibration: A Science-Based Method - Part 2

Jan. 25, 2007
Science-based calibration (SBC) mechanizes the calibration process by removing choices and by forcing the user to substantiate each of the inputs with scientific backup information

Editor’s Note: In Part 1 of this article (Pharmaceutical Manufacturing, January 2007, p. 42), the author introduced science-based calibration (SBC), providing some theoretical background, a summary of the method, an example of its use and a discussion of its advantages. In Part 2, Marbach focuses on the method’s applicability and limitations, as well as the specificity of response.

Click the Download Now button below to access this four-page (1.8 MB) PDF document.

About the Author

Ralf Marbach | VTT Optical Instruments Center