Small Molecule

Traditional, chemically synthesized drugs (typically oral solid dose products) continue to be the dominant drug delivery form, used for a wide range of treatments. Here you will find content about formulations and the manufacturing technology and techniques used to make these popular products

Articles

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Screen Shot 2023 09 06 At 11 17 20 Am
Screen Shot 2023 09 06 At 11 17 20 Am
Screen Shot 2023 09 06 At 11 17 20 Am
Screen Shot 2023 09 06 At 11 17 20 Am

Bridging the gap between R&D and GMP

Companies prioritizing optimized synthetic routes, stable API forms, and verified analytical tools set the stage for phase I clinical manufacturing success
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Shutterstock 2224667693
Shutterstock 2224667693
Shutterstock 2224667693
Shutterstock 2224667693

OSD spreads its wings

Bright ideas are helping drugs and butterflies take flight
Microsoft Teams Image (1)
Microsoft Teams Image (1)
Microsoft Teams Image (1)
Microsoft Teams Image (1)
Microsoft Teams Image (1)

OSD soars: Evolution of oral solid dose technology

In phase 2 of our OSD series, we cover the resurgence of fixed-dose combinations and the pursuit of effective oral delivery for biologics
Microsoft Teams Image (2)
Microsoft Teams Image (2)
Microsoft Teams Image (2)
Microsoft Teams Image (2)
Microsoft Teams Image (2)

OSD soars: The digital metamorphosis

In phase III of our OSD series, we cover what's on the horizon for the digital metamorphosis of drug delivery, including 3D printing and robot pills.
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Pm2303 Hero 854x480 Web
Pm2303 Hero 854x480 Web
Pm2303 Hero 854x480 Web
Pm2303 Hero 854x480 Web

Reproductive plights

There is no rest for reproductive health drugs in post-Roe America
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Pm2303 Hero 854x480 Cover Story
Pm2303 Hero 854x480 Cover Story
Pm2303 Hero 854x480 Cover Story
Pm2303 Hero 854x480 Cover Story

Nevertheless, they persisted

How drugmakers are fighting to keep reproductive health drugs available, safe and legal
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PM2205-HERO-575x327-Operations-copy

Tablet tooling: Don’t let the rust set in

How pharma manufacturers can best protect equipment from corrosion
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Pulling antibiotics from the fire

Can policy reform save a market in peril?
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PM2202-HERO-575x327-Development-copy
PM2202-HERO-575x327-Development-copy
PM2202-HERO-575x327-Development-copy
PM2202-HERO-575x327-Development-copy

The past, present and future of antiviral discovery

New methods and strategies to address the complexities of viral infection offer hope for antiviral drug development
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Minding the gap

As holes in mental health treatment deepen, can pharma fill the voids?
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10 major drugs falling off the patent cliff in 2021

At some point, the patent cliff claims the high-rolling life of market exclusivity for all drugs — and 2021 is, of course, no exception.Although the industry has been flushed ...
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PM2104-HERO-880x500-Operations
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PM2104-HERO-880x500-Operations
PM2104-HERO-880x500-Operations

Back-to-basics on tablet press efficiency

How an objective assessment of equipment’s efficiency can make a big difference
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PM2104-HERO-575x327-Pipeline
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Pipeline snapshot: Two treatments that could change the game for Alzheimer’s

It’s no secret that the pipeline for Alzheimer’s treatments has mostly become a sinkhole for dozens of failed drugs and billions in lost R&D dollars. But with the stakes so high...
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PM2011-HERO-880x500-Culture
PM2011-HERO-880x500-Culture
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PM2011-HERO-880x500-Culture

Improving manufacturing skills in a pandemic world

E-learning has become an important part of the future of solid dose manufacturing
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Pharma’s biggest blockbusters

A look at trends with the industry’s heavy hitters