Multivariate Calibration: A Science-Based Method - Part 1

An alternative approach uses physical methods to estimate the spectral signal and statistical methods to estimate noise.

By Ralf Marbach, VTT Optical Instruments Center

Share Print Related RSS

Editor’s Note: In Part 1 of this article, the author introduces science-based calibration (SBC) and provides some theoretical background, a summary of the method, an example of its use and a discussion of its advantages. In Part 2 (Pharmaceutical Manufacturing, February 2007, p. 44), Marbach will focus on the method’s applicability and limitations, as well as the specificity of response.

Click the Download Now button below to access this five-page (2.4 MB) PDF document.

Share Print Reprints Permissions

What are your comments?

Join the discussion today. Login Here.

Comments

No one has commented on this page yet.

RSS feed for comments on this page | RSS feed for all comments