Optimizing Viral Vector Yields Without Serum

Accelerate early-phase vaccine development with a proven approach to reduce serum use and enhance viral vector yields. Discover how animal-origin-free supplements can improve performance, consistency, and scalability in vaccine development.
March 23, 2026

As vaccine developers transition away from animal serum, identifying reliable, scalable alternatives is critical for early-phase programs. This application note highlights two case studies demonstrating how animal origin–free supplements support adherent Vero and suspension HEK293 cell growth while enhancing viral vector production.

Under reduced-serum conditions, optimized blends increased VSV titers, and targeted supplementation improved adenovirus yields by over 50% compared to controls.

Backed by rigorous quality control and a data-driven Key Driver Identification (KDI) approach, these solutions help reduce variability, improve consistency, and accelerate progress from preclinical development through manufacturing.