Flow-through mAb Polish Purfication

Innovative purification approaches are essential in the rapidly evolving monoclonal antibody (mAb) development landscape, particularly during the polishing process.

In this article, discover how advances in flow-through chromatography methods via hydrophobic interaction chromatography (HIC) and mixed-mode chromatography can enhance mAb polishing by removing challenging impurities and improving product quality.

 Learn from case studies that:

1) address low loading challenges, increasing productivity
2) remove challenging impurities with significant contribution to viral clearance
3) demonstrate a wide operating range for aggregate removal in flow-through mode

Gain confidence in your mAb downstream processes with tools and techniques shared in this article.