Displaying 1–23 of 23 results for PANalytical Inc

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High Throughput Diffraction

(Whitepaper)

PANalytical's X'Pert PRO MPD, equipped with automated sample changer and high speed, high resolution X'Celerator detector can already measure hundreds of full scans every day with a range of additional tools, it provides a solution for high throughput XRD.

A Complete Walk-Up System Solution for X-Ray Powder Diffraction

(Whitepaper)

The Cubix Walk-Up systems comes with the security of 21 CFR Part 11 supporting software, and the possiblity of working in conjunction with many LIMS systems. With new sample handling hardware and simplified user interface for easy access, PANalytical offers high speed, high-resolution XRPD ...

X-Ray Solutions for the Pharmaceutical Industry

(Whitepaper)

This brochure describes the practical advantages of XRPD in the pharmaceutical industry, PANalytical's detector technology and the innovative design of PreFIX optics and stages that makes application switching straightforward and alignment easy, the wide range of applications for the physical ...

Application Study: The Analysis of Pd in Pharmaceutical Materials Using the ...

(Whitepaper)

The Epsilon 5 is a high performance energy dispersive X-ray fluorescence spectrometer specifically designed to achieve the lowest possible LLD's for heavy trace elements such as Cd, Pb, As, precious metals and the lanthanides. A key application capability of the Epsilon 5 is its ability to ...

X-Ray Diffraction in Biomedical Research

(Whitepaper)

In this application note, thin film XRD was employed for qualitative analysis of the chemical and biological properties of biomedical, electrosprayed calcium phosphate coatings. XRD analysis provided in-depth examination of the relationship between processing conditions and the chemical nature of...

X-Ray Diffraction on Aerosol Drugs

(Whitepaper)

In this note, an X-Pert PRO MPD system equipped with an X'Celerator detector was used to analyze the crystal structure of Ventolin and to quantify small amounts delivered by a pressurised metered dose inhaler.

Temperature and Humidity Controlled XRD

(Whitepaper)

The temperature controlled humidity system for X-ray diffraction analysis was applied to measure the influence of temperature and humidity on 4-epi-oxytetracycline in this application note. This compound is used as a standard to control the impurities during the production of antibiotics based on...

Transmission Diffraction: Measurement and Unit Cell Refinement of Lysozyme

(Whitepaper)

In this research, transmission experiments were performed on a hen egg-white lysozyme sample. The high angular resolution of the data enabled cell searching, indexing and unit cell refinement. The lattice parameters determined were in good agreement with the data obtained from single crystal ...

A Technological Solution for Combating Counterfeit Drugs

(Whitepaper)

Compared to other forms of counterfeiting, the production of fake medicines almost certainly has the greatest potential for harming human health. The scale of the problem is immense with, for example, an estimated 2 - 300,000 people dying in China each year as the result of counterfeit medicines....

QbD and Detecting Crystal Polymorphs

(Whitepaper)

No longer just a fingerprinting method, X-Ray Powder Diffraction is becoming a user-friendly PAT tool. This white paper discusses how accessible XRPD systems address the needs of today's pharmaceutical industry, which requires a multi-disciplinary approach to pharmaceutical product design.

PANalytical Inc.

(Product)

Supporting the Pharmaceutical Industry with 21 CFR Part 11 Compliance Readiness

(Whitepaper)

The purpose of this document is to describe how PANalytical systems support system owners meeting the requirements of the 21 CFR Part 11 regulations issued by the United States’ FDA. Design and development of PANalytical systems is done according to ISO9001:2000, ISO14001:1996 and CMM level 3 ...

High-Resolution, High Throughput XRPD

(Whitepaper)

High throughput screening is not commonplace in pharmaceutical development. This application note describes the use of a PANalytical X-ray powder diffractometer for high throuput, high-resolution polymorph screening.

Analysis of Air Filters According to EPA Method 10-3.3

(Whitepaper)

The presence of toxic pollutants in the air has been a subject of research for many years in the United States and countries around the world. This application study demonstrates the performance of the Epsilon 5 EDXRF analyzer according to the EPA method 10-3.3, with the elemental range extended ...

Crystallinity Determination

(Whitepaper)

This note compares the use of three different methods- X-ray diffraction (XRD), near infrared spectroscopy (NIRS) and differential scanning calorimetry (DSC)-for quantifying small amounts of amorphous material in a crystalline matrix, and vice versa.

X'Pert Pro Alpha-1

(Whitepaper)

The X'Pert Pro Alpha-1 diffraction system is suitable for solving structures from powder data, searching for polymorphic phases where peak overlap is a hinderance, studying nanomaterial peak profiles to extract crystallite size, dislocation densities and preparing materials for synchrotron beam time

X'Pert PRO MPD: Multi-Purpose X-Ray Diffractometer

(Whitepaper)

The X'Pert PRO MPD x-ray powder diffractometer offers a variety of optics, sample stages, changers and detectors allowing the optimal combination of resolution and data collection speed for every sample. A flexible optical bench allows rapid reconfiguration and the system meets the most stringent...

Determination of Fe in Milk Powder

(Whitepaper)

Milk is a source of essential nutrients for humans, therefore the elemental analysis of milk powder is very important. Of all the metals, iron is one of the most known as a nutrient. Measurements in this study were performed using the MiniPal 2 benchtop EDXRF spectrometer.

Trace Element Analysis of Organic-Rich Samples Using Axios with Pro-Trace

(Whitepaper)

Organic-rich materials have a variety of uses as fuels, together with a range of waste materials used as alternative fuels; and as fertilizers, for example compost and sewerage sludge. Accurate trace element analysis of these materials is becoming increasingly important as governments tighten ...

Quantitative XRD: Detection of Low Amounts of Crystalline Impurities for ...

(Whitepaper)

In this example application, standard samples of Form 1 of an API were spiked with low levels of the polymorph Form II. XRPD was used to calibrate an analysis, programmed in PANalytical's X'Pert Industry software, which could then be used for manufacturing process control to ensure that the right...

Quantitative Evaluation Of Pharmaceutical Solids

(Whitepaper)

This research investigates combinations of optics and diffraction methodologies that would allow an accurate quantification of an API in a typical pharmaceutical oral dosage form. All methodologies investigated allow non-destructive testing for the unifromity of the API content in a batch. This ...

Crystallite Size Determination

(Whitepaper)

This note describes the use of Rietveld method for determining crystallite sizes of pharmaceutical powder samples. In contrast to Scanning Electron Microscopy that could hardly detect changes in the particle size, XRD clearly showed the decrease in crystallite size with increasing milling time of...

A Technological Solution for Combating Counterfeit Drugs

(Whitepaper)

Compared to other forms of counterfeiting, the production of fake medicines almost certainly has the greatest potential for harming human health. The scale of the problem is immense with, for example, an estimated 2 - 300,000 people die in China each year as the result of counterfeit medicines. ...

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