White paper: Approaches to alleviating subcutaneous pain at injection sites
Feb. 20, 2024
High concentration mAbs can create challenges for subcutaneous injection, namely pain at the injection site. This peer-reviewed article compares buffer formulation options, and an excipients selection strategy, in reducing injection-site pain.
mAbs delivered via subcutaneous (SC) injection provide numerous patient benefits and are currently the most common route of self-administered drugs. Yet these therapies must be formulated at high concentration, which may cause increased injection-site pain.
This article will discuss the use of citrate in SC formulations as compared to other buffers, as well as a formulation and excipients selection strategy that can be used to mitigate the risk of injection-site pain due to buffer, pH, and viscosity.
Manual weighing processes can result in significant waste due to errors, overfilling, and underfilling, resulting in bad batches and product recalls.METTLER ...
RapidCal™ Tank Scale Calibration is the new method for tank, reactor, hopper and silo scales. It is fast, traceable and doesn’t require special material or cleaning.
Weighing is a critical process within many operations. Ensure that your equipment is meeting your process requirements and delivering the quality you expect.
Waste is one of the most complex hurdles to achieving your sustainability goals and managing costs. Step one to eliminate waste is to confidently match your equipment to your ...
