Koch Membrane Systems, Inc.

Dec. 17, 2007
Membranes Facilitate Separation of Antibiotics and APIs

Koch Membrane Systems, Inc. (KMS), a developer and manufacturer of membranes and membrane filtration systems, will showcase its FLUID SYSTEMS SPIRAPRO TFC line of spiral-wound membrane elements and its SelRO nanofiltration elements in booth #2515 at INFORMEX 2008 from Jan. 29-Feb. 1 in New Orleans, La. 

Suited for desalting and the separation of antibiotics and APIs, the FLUID SYSTEMS SPIRAPRO TFC elements utilize a proprietary, polyamide thin-film composite membrane with a sanitary spiral-wound net outerwrap. The molecular weight cut-off for the TFC SR3 is such that the membrane will pass monovalent salts like sodium chloride, yet provide high retention of multivalent ions and uncharged organic solutes. Retention of sugars, including lactose, typically exceeds 99%. These elements can be useful for separating small molecules from chromatography effluent or other intermediate purification processes.

The SelRO nanofiltration membranes provide chemical and thermal stability to satisfy the demanding requirements of processes involving high and low pH, high temperature and organic solvents media. Most nanofiltration membranes previously available were limited to aqueous applications within a pH range of 2 through 11, insufficient for certain pharmaceutical and fine chemical applications with aggressive cleaning requirements. However, SelRO acid/base stable membranes can be operated within a pH range of 0-14.

For more information about the SPIRAPRO TFC SR3 and the SelRO nanofiltration elements, please visit KMS at booth #2515 at INFORMEX 2008.