Preparing samples by clarification is an essential step prior to nearly all analytical techniques, such as high pressure liquid chromatography (HPLC). Sartorius has developed the manually operated Claristep filtration system consisting of a station and filter units for clarifying samples prior to analysis.
The Claristep station consists of a base, a lid and an exchangeable tray for accurate positioning of sample vials. The patent-pending design features grooves that automatically guide the filter unit caps into the correct positions for simultaneous and accurate cap closure.
Claristep enables up to eight samples to be simultaneously filtered without any power supply or a vacuum pressure source. Single-use Claristep filter units with RC membranes are designed for sample volumes of 60 μL to 600 μL. Their hold-up volume is less than 30 μL. The units have been optimized for solvents and aqueous solutions and provide maximum chemical compatibility as well as low non-specific binding of analytes. The contact time of the samples with the filters and the caps is extremely short, ensuring optimal, contamination-free results. Filtrates are collected in any 12 × 32 mm outer diameter vials of the user’s choice based on the analytical method to be performed.