Pall Corp.

April 30, 2007
Ultrafiltration Cassettes Reduce Extractables

Pall Corp. recently introduced the new Omega T- Series Membrane Cassettes to offer enhanced processing efficiencies and greater product recovery. The new cassettes are constructed with high-performance materials that reduce extractables to deliver high-purity biological solutions. These cassettes assure effective mass transfer of proteins, which is critical for biotech manufacturers given the significant cost of even minimal volumes of purified protein solutions used in downstream drug production. Pall also introduces single-use Minimate II encapsulated membrane cassettes, the latest addition to the company’s line of single-use technologies.

The Omega T-Series cassettes incorporate Pall’s high-yield Omega membranes and a new polypropylene screen to increase processing flux rates and product recovery. Materials of construction chosen for the Omega T-Series cassettes ensure a low level of extractables. This reduces the amount of rinsing volumes that are required prior to cassette use, saving time and material costs.

The cassettes feature a new exterior design with deeper notches so that cassettes fit more snugly and securely in the holders. The more rigid encapsulation material reduces over-torquing issues that compress membrane channels and impede product flow, which might occur with traditional manual cassette holders.

The Omega T-Series cassettes are available in fully scalable formats to facilitate their use in a wide variety of bioprocessing applications. Offered in four sizes, 200 cm², 0.1 m², 0.5 m², and 2.5 m², the cassettes integrate well with most standard stainless steel holders.

Pall also offers two smaller sizes of the Omega T-Series cassettes in the Minimate II single-use format module. Minimate II cassettes do not require torquing, and as single-use units, these cassettes are easy to use and install, resulting in additional efficiency benefits.