Mitigating Process Risk and Cost by Immobilizing Activated Carbon


Drug manufacturers use activated carbon to reduce reaction impurities and de-colorize active ingredients. Its use, however, may result in operator exposure to carbon dust, high maintenance and cleaning costs, and difficulty in removing carbon from the process stream. 3M Purification's Zeta Plus Activated Carbon cartridge series minimizes this risk by immobilizing the activated carbon. This paper describes typical pharmaceutical applications for Zeta Plus, how the optimal carbon type and media grade are chosen for those applications, and best practices for carbon filtering during process scale-up.