Single-Use Products: Tubing Sets vs. Manifolds

Unlike traditional process tubing sets, which are susceptible to leakage and entrapment issues, single-use manifolds and assemblies feature molded connections to ensure the purity of the fluid path. AdvantaPure's John Stover explains.

Satellite Process Assurance Hub (SPAH) Drug Facility Layout

Two years ago, Joseph Lam, managing director of Beacons Pharmaceuticals Ltd., a leading generics manufacturer in Singapore, was awarded a U.S. patent for a novel drug facility layout, SPAH. Mention of this provoked some surprise from experts in the U.S. engineering and construction world. They had never heard of a plant layout, however creative, being patented.

Market Intelligence Report: Tracking Your Workforce

Genentech Oceanside’s Continuous Improvement Journey

A talk with associate director of manufacturing Kawa Chiu about initial, and lasting, Right First Time successes.

Open Season for PAT

ABB’s Thomas Buijs explains how an open architecture will empower PAT devices.

Today’s Wireless Pharma

Honeywell’s Steve Zarichniak illustrates how the wireless facility is already being realized.

Oxygen Sense and Sensibility

Dissolved oxygen monitoring is critical to biopharma processes, and the Visiferm DO provides accurate, and rugged, measurement regardless of flow or media, says Amber Ratcliff of Hamilton Company.

Good Engineering Practice in a QbD Time

ISPE’s new baseline guide for Good Engineering Practice has just been released, and NNE Pharmaplan’s Peter Christiansen outlines key new concepts.

A Transparent Case for Glass Doors

When it comes to pharmaceutical doors, more and more are looking like windows—ie, they’re glass, says Rytec CEO Don Grasso.

Proactive Contamination Control

Smart manufacturers are heading off microbial issues by mapping their facilities and taking other proactive measures that go well beyond contamination control of the past. Tina Sturgill of Celsis Analytical Services explains.

Logging Temperature and More, Wirelessly

Mesa Labs’ DataTrace is a wireless data logger that, as Dale Ashley shows us, can follow your product just about anywhere.

Q&A on Pharmaceutical Quality by Design - FDA's Afnan on QbD and Final Release Testing

At Emerson Users Exchange 2009, FDA Senior Fellow Ali Afnan discussed QbD and responded to a question from the audience about pharmaceutical quality by design,and whether QbD submissions to the FDA so far had reduced product release testing.

Ali Afnan on Real Time Release and End of Line Testing

At the 2009 Emerson Users Exchange, Ali Afnan, senior Fellow at FDA's Center for Drug Evaluation and Research, discusses real time release, highlighting Aventis work with API and finished drug manufacturing. End-of-line testing isn't bad, he says, but it needs to be used for different reasons.

Gawayne Mahboubian-Jones on PAT's Business Case

Gawayne Mahboubian-Jones, Product Development Manager at Optimal Automation, discusses the need for creating a "process trajectory," and the role that process analytical technologies can play in drug development and manufacturing. Optimal's SynTQ platform has been used in numerous installations and is now bundled into some Emerson products. He spoke at a life sciences symposium at the Emerson Users Exchange in 2009.

Lilly Layoffs Reflect New Corp. Culture

Lilly is the 10th largest pharmaceutical company in the world. Its size, success and corporate culture have long enabled many employees to spend their entire professional careers there. But the 'Lilly Lifer' corporate culture is changing.

PAT and the Plant: An Overview of Tools and Applications

CAMO Software's Katherine Bakeev (former principal scientist for PAT at GlaxoSmithKline) speaks on PAT and multivariate analysis. While the start of this video is broad, the end illustrates how PAT fits into the IT, control, engineering, and operational framework of a plant.

The Triple Bottom Line: A Strategy Tailor Made for Pharma

CEO of Advanced Electron Beams, Mitch Tyson, discusses how pharma companies can strengthen their organizations, and their balance sheets, by adopting the TBL.

Podcast: This Is Not Your Father’s Coriolis: Flow Measurement Goes Micro

We speak with Endress + Hauser’s Joerg Herwig about his company’s partnership with MEMS specialist Integrated Sensing Systems (Issys) and how E+H aims to take all of its products to the micro scale.

Outsourcing GMP? Yes, If You Can Manage the Risk

Outsourcing non-core GMP activities can make sense, but those who do must tread cautiously. Know the risks, manage them, and have a sound mitigation strategy. This video is the second in a series with outsourcing expert Rakesh Kishan, CEO of UMS Advisory, Inc.

Novel Concept: Outsourcing for the Good of Your Core Employees

Many manufacturers may not realize that outsourcing can be an opportunity to empower core employees, expand their work roles and relationships, and give them new career options. Companies that approach outsourcing with the good of core employees in mind will succeed. Those that don’t risk alienating their best and brightest. This video is the third in a series with outsourcing expert Rakesh Kishan, CEO of UMS Advisory, Inc.