September 2005 Issue
Pharma ERP has been an underachiever for years; savvy drug makers are turning that picture around by connecting ERPs more closely to the plant floor.
PATs got momentum, but could a lack of capable professionals slow it down?
Pharmaceutical process control is advancing, but will its progress be fast enough?
PAT is the missing link in the evolution of pharmaceutical process control, but industry must act on the opportunity to realize expected gains.
The future is now for process monitoring via wireless instrumentation, while wireless process control looms.
The mixing of biological products is delicate business, but concerns about shear sensitivity can be overblown. Rational process development, rules of thumb and tools like CFD can lead to fearless mixing.
Filtration can be the quickest, most cost-effective means to achieve sterilization for large volumes of simple buffers or aqueous solutions. However, finding the right flow rate and filter sizing is essential to meeting FDAs aseptic guidelines.
Coatings an unforgiving process, but a clear understanding of key parameters, and straight shooting, can help ensure success.
As evidenced by the proliferation of pharmaceutical R&D and manufacturing facilities in Research Triangle Park and the Piedmont Triad, people go where the science and opportunity are.