Novel Analytical Approaches to Aminoglycoside and Macrolide Antibiotic Determination


Presented here are HPLC-CAD methods to measure aminoglycosides (either individually or globally); an improved, robust method using HPLC-coulometric detection for azithromycin and gradient HPLC-coulometric array detection for the measurement of impurities at <0.1% in lincomycin, amoxicillin, aza-erythromycin and the peptidergic antibiotic vancomycin.