Use CFD to Improve Crystallization

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Overview:

Drug manufacturers charged with developing, scaling up or scaling down any process involving crystallization face major challenges, given the industry's current understanding of flow characteristics and crystallization kinetics. In this article, Kumar Dhanasekharan, Ph.D., technical specialist with the computational fluid dynamics (CFD) specialist Fluent, Inc., shows how modelling crystallizers using CFD can help improve process understanding, control crystal size distribution (CSD) and improve pharmaceutical crystallization results.