Bruker's Matrix-F process FT-NIR spectrometer

Bruker Optics and Dr. Schleuniger Pharmatron are collaborating on an at-line PAT system called StepOne. The system combines the proven automation of Dr. Schleuniger Pharmatron's AutoTest 4 tablet testing system (pictured above) with the performance of Bruker Optics' FT-NIR technology.

The process FT-NIR spectrometer Matrix-F spectrometer (photo at right) or its laboratory version, MPA, can be coupled to the Dr. Schleuniger Pharmatron Autotest 4 tablet tester for diffuse reflectance FT-NIR measurements. The Autotest 4 provides tablet weight, thickness, diameter, and hardness measurements and the FT-NIR provides rapid, non-destructive potency and content uniformity determination. The StepOne system is capable of testing a wide variety of tablet shapes. Samples can be loaded directly from a press or manually placed in the sample feeder.

Traditional content uniformity analysis has been performed by HPLC, which is a destructive, slow and generally laboratory-based technique. Near Infared spectroscopy has proven to be a cost- and time-efficient alternative, providing valuable analysis through the pharmaceutical manufacturing process.

U.S. contact info. for Dr. Schleuniger Pharmatron:
Dr. Schleuniger Pharmatron Inc.
25 Sundial Avenue, Suite 315
Manchester, NH 03103 USA
Phone: +1 603 645 67 66
Fax: +1 603 645 67 26
E-mail: info@pharmatron.com
Homepage: www.pharmatron.com

Swiss Headquarters Homepage: www.pharmatron.ch

Company Information

19 Fortune Drive
Billerica, Mass. 01821 (see map)
Contact Name: A. Haydar Kustu, Marketing Manager
Phone: (978) 439-9899
Fax: (978) 663-9177
email: haydar.kustu@brukeroptics.com
Website: www.brukeroptics.com/pr