Tuesday, May 13, 2008

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Articles (17) White Papers (7) News (34) Products (23)

Topic: Drug Delivery

Heparin Drama Underscores Need for More FDA Funding and Supplier Oversight
PharmaManufacturing.com
April brought painful reminders of the human cost of pharmaceutical quality control problems, the need for more FDA resources and better supplier risk management. It also highlighted the tenuous relationship that the Agency and its leaders already have with many U.S. lawmakers.

Drug Delivery and QbD: A Collision of Lifecycles
PharmaManufacturing.com
While the industry waits patiently for ICH Q10 to show us the way to incorporate ICH Q8 and Q9, the basic framework already exists in FDA’s Quality System Regulations for devices.

Compressing Force: Myth vs Reality
PharmaManufacturing.com
Compressing force is a dynamic number recorded as the attempt to maintain two target values in close tolerance

Blog: Poor Emil’s Almanac
PharmaManufacturing.com
Never known for his shyness, NIR expert Emil Ciurczak shares his unedited and uncensored perspectives on the industry he knows so well. Write in and let him know what you think.

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White Papers: In depth research


Title Author Date
Nanoparticles in Pharmaceutical Manufacturing NETZSCH Fine Particle Technology, LLC 04/14/2008
The paper explores the rapidly expanding role and significant performance advantages of nanoparticles in pharmaceutical applications. It provides an overview of nanoparticle uses in applications including diagnostic products, product packaging and biomarker discovery, as well as an extensive look at nanoparticle use in drug delivery. The paper also describes the ability to create nanoparticles efficiently and economically with media milling. 
The Impact of Nanotechnology in Drug Delivery: Global Developments, Market Analysis, and Future Prospects NanoMarkets, LC 11/01/2007
This report by NanoMarkets, LC includes an overview of nanoenabled drug delivery technologies, commercial applications and information on the companies pursuing them, information on nanotechnology initiatives and regulation in major international markets (North America, EU, Japan, Israel, etc.), as well as eight-year worldwide forecasts on the industry’s anticipated growth and timing thereof. 
RABS: Injecting Change into Syringe Drug Delivery Joerg Zimmermann, head of production, Vetter Pharma 08/14/2006
Routine administration of injections involves several risky steps: Was the needle really sterile? Is that drug really in order? Was the dosage accurate? And what happens to those few drops of costly drug that remain at the bottom of the vial? Joerg Zimmerman of Vetter reveals an innovative method of aseptic filling for syringes, which reduces such risk involved in intravenous drug delivery systems. 
Aqueous Film Coating of Tablets in a Side-Vented Pan Coater Mirja Ruotsalainen, Helsinki University 02/20/2006
This 53-page thesis by Mirja Ruotsalainen at Helsinki University, Finland, examines the impact of coating and storage on surface morphology, moisture control and stability. 
Phase Transformation in Solid Pharmaceutical Materials Denny Mahlin, Uppsala Faculty of Pharmacy 02/20/2006
This 72-page PDF, a dissertation by Denny Mahlin at Sweden's Uppsala Faculty of Pharmacy, discusses results of using atomic force microscopy and other techniques to study solid mixtures for solid dosage forms.  
CDER's 2004 Report to the Nation: Improving Public Health Through Human Drugs FDA's Center for Drug Evaluation and Research 08/23/2005
This 66-page report discusses what was accomplished by FDA's Center for Drug Evaluation and Research in 2004, and looks at the initiatives it will be tackling this year and in the near future. 
Pharma 2010: The Threshold of Innovation IBM Business Consulting Services 10/19/2004
The pharmaceutical future belongs to companies able to deliver "targeted treatment solutions," claims this visionary report, part of IBM Business Consulting Services Pharma 2010 series. This brief but sweeping report focuses on how firms can get ahead and stay ahead in the targeted treatment game. 
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