News

Posted On: 07/26/2007

cGMP Facility Constructed at University of Iowa

PharmaManufacturing.com

The University of Iowa Center for Biocatalysis and Bioprocessing unveiled its new Current Good Manufacturing Practices (cGMP) facility at an official ribbon-cutting ceremony on July 9, 2007.  Designed by CH2M HILL Lockwood Greene in conjunction with Rohrbach Associates PC and Alvine & Associates, Inc., the facility offers state-of-the-art manufacturing of products suitable for clinical use.

CH2M HILL assisted in the renovation of an existing building into a cGMP clinical-scale bioprocess manufacturing suite of facilities. The manufacturing suite houses microorganism fermentation and product recovery operations, based on three fermentors. An adjacent building houses cGMP product purification operations.

“The primary challenge for our design team was to develop a flexible plan that would meet the universities operational objectives and equipment space needs, within limited space, and still provide the level of environmental segregation needed to ensure good operational flow and regulatory compliance,” said Robert Orgera, CH2M HILL’s principal architect on this project.

As the bioprocess designer and cGMP consulting and process engineer, CH2M HILL was responsible for developing facility operations, including layout, operational follows and process equipment and utility requirements. Additionally, CH2M HILL engineered process utility systems, established good manufacturing practices compliant architectural materials, provided design coordination through design and bid phases and provided design review for cGMP compliance.