Articles

Tools to Keep Pharma Fluids Flowing

An assortment of pump and valve innovations help provide clean process efficiencies.
Post Date: 01/15/2013
Author: Katie Weiler, Managing Editor

Trouble Shooting Depth Filtration

Some common scenarios (and their root causes)
Post Date: 10/03/2012
Author: Brittany Nixon, 3M Purification

Are Single-Use Standards Stuck? And Is That a Bad Thing?

Efforts to enact meaningful standards for single-use bioprocessing technologies move at a snail's pace, with no clear path forward, experts say.
Post Date: 06/21/2012
Author: Paul Thomas, Senior Editor

Biopharma's Flexible Imperative

Business forces, bioterror and pandemic risks demand new approaches to manufacturing.
Post Date: 06/06/2012
Author: Robert F. Dream, Principal, HDR Company, LLC

Bioprocess Filter 411: A Look at New Products for 2012

Solution providers churn out new and improved products in the heated market for upstream and downstream filtration technology.
Post Date: 05/08/2012
Author:

With a Full Range of Products, EMD Millipore Turns Its Attention to Solutions

The company aims to leverage the expertise it has always had in-house, yet hadn’t fully capitalized on with the pharma industry, says VP Christophe Couturier.
Post Date: 05/02/2012
Author: Paul Thomas, Senior Editor

The Pulse of Pharmaceutical Manufacturing

The big picture has changed very little in ten years. While pointing out root causes, observers also see reasons for optimism.
Post Date: 04/04/2012
Author: Agnes Shanley, Editor in Chief

Imaging the Blending Process

Hyperspectral imaging can be used to optimize blending, by monitoring the distribution of excipients and APIs in formulation.
Post Date: 01/03/2012
Author: Gabor Kemeny and Gina Stuessy, Middleton Research

Process Validation Guidance: A Bad Fit for Aseptic Processing?

“Science-based” is well and good, but FDA’s guidance may create confusion.
Post Date: 09/28/2011
Author: Paul Thomas, Senior Editor

Risk Management in Pharmaceutical Microbiology

At look at how HACCP and FMEA can make a difference in the pharma micro lab.
Post Date: 09/21/2011
Author: Tim Sandle, Head of Microbiology, Bio Products Laboratory

Therapeutic Dose: Facilius per Partes in Cognitionem Totius Adducimur

We are more easily led part by part to an understanding of the whole. –Seneca
Post Date: 07/20/2011
Author: Emil W. Ciurczak, Contributing Editor

Maintaining Integrity: Effects of SIP Sterilization on PTFE Valve Diaphragms

As PTFE diaphragms are subjected to more aggressive sterilization and cooling conditions, they are more prone to failure from cracking, splitting, deformation and SIP steam-induced blisters.
Post Date: 06/01/2011
Author: Steve Pitolaj, Principal Engineer, and Jim Drago, P.E., Garlock Sealing ...

Bioprocess Filtration: Debating Post-sterilization Integrity Testing

At PDA 2011, at issue was whether current EMA guidelines are rational or risky; also, a look at new filtration products on the market.
Post Date: 05/18/2011
Author: Paul Thomas, Senior Editor

pH: Are You in Control of a Moving Target?

pH is a deceptively simple measurement; its control can be extremely challenging in both upstream and downstream biopharmaceutical manufacturing.
Post Date: 04/05/2011
Author: Jim Wilkins, Sensorin, Inc.

Controlled Ice Nucleation Moves into Manufacturing

Two viable techniques exist for better lyo control in commercial processes, says UConn’s freeze-drying guru.
Post Date: 02/15/2011
Author: Paul Thomas, Senior Editor

Microbial ID Habits, Under the Microscope

A look at what microbiologists do and want, by the numbers, and commentary from consultant Pascal Yvon.
Post Date: 09/10/2010
Author: Paul Thomas, Senior Editor

Continuous Low Moisture Wet Mass Granulation: A Demonstration of Potential

In text, illustrations, and video, Bren Kindelsperger makes the case for continuous wet mass granulation as an alternative to traditional methods of tablet and pill formulation.
Post Date: 07/21/2010
Author: Dr. Bren W. Kindelsperger, Readco Kurimoto LLC

PDA 2010: A Glimpse into the Single-Use Future

Maik Jornitz envisions the vast potential of single-use biotechnologies.
Post Date: 04/06/2010
Author: Paul Thomas, Senior Editor

Taking the Plunge to Harmonize Pharmaceutical Regulations

Within the past five years, more of world's regulatory agencies and pharmacopeias have gotten on the same wavelength.
Post Date: 03/04/2010
Author: Agnes Shanley, Editor in Chief

A Business Case for Isolation Technology

Every sterile facility is unique, but a recent Jacobs study suggests that advanced isolation technology pays dividends in the long run.
Post Date: 01/11/2010
Author: