Articles

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  • Applying Lean Principles to Facilities and Workplace Design

    When it was published in 1996, the first edition of Facilities & Workplace Design: An Illustrated Guide enjoyed strong demand. However, the book went out of print when the publisher ceased operations. Now, Quarterman Lee, the book's primary author and president of Strategos, Inc., is producing a second edition; here he makes the first edition available for download.

    Quarterman Lee, President, Strategos, Inc.
    09/11/2006
  • Taking Pharma's Pulse: What's Your View of the Industry's Economic Outlook?

    How do you view your company's and the industry's economic health? Which areas were key investment focuses for 2006, and what do you think the future will hold? Please take a few minutes to share your views in our 2006 Capital Investment survey. All results will remain confidential and will never be shared with any other organization.

    09/11/2006
  • Pfizer's Warman and Pillai Lead AutomationXchange PAT Panel

    Pfizer's Jeff Miller, Martin Warman and Lou Pillai participated in a PAT Roundtable at AutomationXchange and hosted by Control magazine. Their mission, in large part, was to illuminate the differences between PAT and process analyzers.

    08/31/2006
  • Tales from the Front: Applying Fieldbus at Genzyme, Part 1

    Where orphan drug manufacturing is concerned, waste is the real enemy. Rather than choosing sides, Genzyme is using all competing Fieldbus protocols in a biopharma manufacturing suite whose products combat a very rare, often fatal disease.

    William T. Dolan, P.E., Genzyme Corp.
    08/31/2006
  • NeSSI and PAT Work Together in Pharmaceutical Manufacturing

    The Center for Process Analytical Chemistry's New Sampling/Sensor Initiative (NeSSI) aims to reduce the footprint of analyzer systems. Thus, it complements Process Analytical Technology, potentially increasing analyzer up-time and providing more process information.

    David M. Simko, Swagelok Co.
    08/31/2006
  • Therapeutic Dose: Avoiding the “Cool Hand Luke” Effect

    Isolation and too narrow a focus limits possibilities — for your career and life, your organization, and the industry. Sure, you may be doing your job right, but are you doing the right job?

    Emil W. Ciurczak, Cadrai Technology Group
    08/25/2006
  • Using MEMS to Control Blending at AstraZeneca

    Nearly half of pharmaceutical solid dosage form manufacturers say that blending is a major cause of variability in their manufacturing processes. In this article, two AstraZeneca senior scientists discuss controlling blending outcomes using MEMS-based NIR spectrometers.

    Peter J. Brush, Ph.D., and Albert W. Alexander, Ph.D., both senior scientists at AstraZeneca Pharmaceuticals
    08/21/2006
  • QbD Takes Biopharma by Storm

    Quality by Design has lost its buzzword status as it becomes a reality for more biopharma companies. Contributing Editor Angelo De Palma examines how Wyeth, Schering and other firms are advancing the concept, and interviews FDA’s Moheb Nasr for his perspective.

    Angelo De Palma, Ph.D., Contributing Editor
    08/21/2006
  • Getting the Most from Coriolis Flowmeters in Pharmaceutical Processes

    Coriolis flowmeters can, or should, occupy many important positions in the pharmaceutical industry because of their natural compatibility with high-purity processes. However, they may not be the best choice for every flow measurement application.

    Vince Salupo, Eli Lilly & Co. and Franki Parson, Emerson Process Management, Micro Motion Division
    08/16/2006
  • Understanding Variability, its Sources and its Impact on the Pharma Supply Chain

    How one pharmaceutical company used the fundamentals of variability analysis to analyze release and stability failures, gain control of its supply chain, and save millions of dollars by identifying and eliminating the causes of those failures.

    Fernando Portes, Principal Project Manager, Best Project Management
    08/16/2006
  • When Less is Much, Much More

    Microreactors are challenging the concept of "economies of scale."

    Angelo De Palma, Ph.D., Contributing Editor
    08/08/2006
  • Organichem Lays a Foundation for Growth

    A new building management system has helped the contract manufacturer automate pressurization control and expand potent compound manufacturing.

    Paul Thomas
    08/08/2006
  • Cook Pharmica Serious about Developing Expertise Locally

    Between establishing a biotech internship program with Indiana University and co-creating the Indiana Life Sciences Education and Training institute, Cook Pharmica is putting its money and efforts right where it said it would.

    08/07/2006
  • Contract Research Drives China's Pharma Sector

    Contract research is both a vehicle for Chinese pharmas to expand their R&D expertise and quality levels, and a bridge for them to enter global markets.

    Yibing Zhou, BioPlan Associates, Inc.
    08/07/2006
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