2006 TOTY Finalist Profiles: Wyeth Excellence in Operations Team, Pearl River, N.Y.

By Paul Thomas, Managing Editor

PharmaManufacturing.com

Under pressure to manage costs, Wyeth’s Excellence in Operations team has re-energized an entire facility.

Turning the Ship Around in Pearl River

Editor's Note: To read the introduction to all five Team of the Year Finalists' stories and access links to the other teams' profiles, click here.

For many people, Centrum vitamins and dietary supplements are as much a part of the morning ritual as that first cup of coffee. The 25-year-old brand remains as strong as ever, but, over the past few years, the costs of making the product have increased by 45%. Wyeth Consumer Healthcare, which manufactures Centrum at its facility in Pearl River, N.Y., had exhausted every conceivable measure to rein in production costs. “Every year we’d take a little bit away here and there, and cut one or two jobs, until we realized that we were as lean as we were going to get for the way we were working ,” says Elizabeth Twomey-Galvin, senior director of strategy and business process management. “We were going to have to look at an [entirely] different way of doing business.”

Management had never said “do or die,” says Twomey-Galvin. “But we decided that we would give ourselves one year to turn this situation around,” she says.

A team of 16 people was established to lay the groundwork for streamlining and optimizing manufacturing and packaging operations, in an initiative called “Excellence in Operations.” The core group included planners, supervisors, department heads, Quality personnel and two consultants from Value Innovation Partners (Haverhill, Mass.), an operational improvement firm that espouses Lean Six Sigma practices.

Within three weeks, the team had constructed 14 value stream maps, which would help to analyze operations and spotlight wasteful or unproductive processes. Eight sub-teams were formed to address key process bottlenecks and issues that had the greatest impact on product reliability and cost:

• set-up time reduction (one team each for packaging, compression and coating);
• total productive maintenance (TPM) for compression and coating;
• demand and operations planning;
• packaging throughput and OEE;
• raw material quality variability;
• root cause analysis.

Members from all four of the site’s core functional groups — Manufacturing, Quality, Packaging and Technology — were represented on the core team, and on each of the sub-teams. “Leads” and “owners” from the eight teams met weekly with Twomey-Galvin to coordinate and prioritize projects, and once a month with an executive steering committee. The teams were given few instructions other than that they all had blank slates to work with. No idea would be dismissed.

One year later, now that the initiative’s first phase has been completed, Centrum’s manufacturing is altogether different:

• A pull manufacturing system has been instituted, resulting in significant reductions in inventory and other efficiencies. Manufacturing is paced according to a weekly packaging schedule.



• Centrum cycle time has been cut from 33 days to 11, well within reach of the organization’s “single-digit cycle time.”



• Direct labor has been reduced by 24%, indirect labor by 11%, accounting for annualized savings of $4.6 million.



• The percentage of lines shipped complete stands at 98.9%, compared to 96.9% previously.



• Safety remains exceptional, with more than one million hours worked without a lost time or restricted work injury.

There’s a renewed sense of pride and optimism in Consumer Healthcare, which has carried over into Pearl River’s R&D and Vaccines units as well. “We want to be the premier site in the Wyeth network,” says Andrew Espejo, director of Centrum manufacturing.

“This has been a very difficult culture change for us, but everyone in the factory has embraced it with enthusiasm and a spirit of cooperation,” adds Joe Vitanza, managing director of the Consumer Healthcare business. “We know what we need to do, and we are pulling together as a team.”

No one would have believed this a year ago, especially not the Centrum operators, who had worked an average of 22 years for the company. “We’re still struggling with changing the culture,” Espejo says. “It’s a huge boat to turn around. But the momentum is there.” Cassandra Coffman, senior manager of Continuous Improvement, has spearheaded the site’s efforts to get the shop floor involved.

No flavor of the month

To overcome the doubters, Consumer Healthcare’s management made clear from the start that they were serious about change. They instructed each of the 70 or so members of the core team and sub-teams — more than 50 of them from the shop floor — to set aside four hours a day for 13 weeks to work on Excellence in Operations projects. No other meetings were to be scheduled during this time, and workers were expected to find ways of managing their “day jobs” while contributing to the project.

“This was a little stressful in the beginning,” says Farooq Moatter, director of Quality Assurance. “But we had to make sure that people understood that the project wasn’t just the flavor of the month.”

Pearl River quality control manager Heather Jager and Jim Livolsi, formerly the associate director of validation, try their hands at Stickle Bricks for a training exercise on manufacturing efficiency.

Getting broad representation from the shop floor was critical. The team also relied heavily on metrics. In the beginning, the site tracked more than 50 KPIs — some daily, others weekly and monthly. Some metrics have since been discontinued while others are added as areas of focus change. Ultimately, the site hopes to have a handful of key measures that will drive the business.