Full Name: Clarisolve Depth Filters
Debut: September 2013
Field Position: Downstream bioprocessing
Skill Set: Efficient single-stage clarification of pretreated feed streams; gradient density structure designed specifically to common feed stream particle size distributions.
Player’s Profile: Clarisolve depth filters eliminate the need for centrifugation which enables implementation of a fully single-use process train, and reduces pre-use flushing requirements. This technology was developed to address the shortcomings of traditional downstream clarification approaches when processing high cell density and high-product titer cell cultures.
Coach’s Notes: ”Until now, higher titers coming from upstream bioreactors have posed a challenge to conventional approaches to clarification,” described Vin Donovan, Vice President of Biopharm Process Solutions, EMD Millipore. “With Clarisolve® depth filters, our customers can now take full advantage of high density pretreated feed streams and improve overall process economics.”
Scout’s Notes: “Delivers improved volumetric capacity and reduced turbidity over any currently available depth filtration technologies.”